Pub. Date : 1983 Dec
PMID : 6140086
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Dietary orotic acid enhances the incidence of gamma-glutamyltransferase positive foci in rat liver induced by chemical carcinogens. | Orotic Acid | gamma-glutamyltransferase 1 | Rattus norvegicus |
| 2 | Feeding male Fischer F-344 rats for 5 weeks a diet containing 1% orotic acid, a precursor for pyrimidine nucleotide biosynthesis, resulted in an increased incidence of gamma-glutamyltransferase (EC 2.3.2.2) positive foci induced by chemical carcinogens including 1,2-dimethylhydrazine, diethylnitrosamine, benzo[a]pyrene, and aflatoxin B1. | Orotic Acid | gamma-glutamyltransferase 1 | Rattus norvegicus |
| 3 | Some of the possible mechanisms by which orotic acid enhances the incidence of gamma-glutamyltransferase positive foci by carcinogens are discussed. | Orotic Acid | gamma-glutamyltransferase 1 | Rattus norvegicus |