Title : Successful treatment with sodium valproate of a patient with Cushing's disease and gross enlargement of the pituitary.

Pub. Date : 1984 Dec

PMID : 6097074






2 Functional Relationships(s)
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1 As sodium valproate is known to induce a decrease of plasma ACTH in Nelson"s syndrome, it is proposed that large tumours present at the time of diagnosis and those appearing after adrenalectomy may represent the spectrum of a single disorder. Valproic Acid proopiomelanocortin Homo sapiens
2 A prospective trial to study the effects of sodium valproate and other neurotransmitter modulating agents on the size and endocrine function of ACTH secreting macroadenomas is urgently needed. Valproic Acid proopiomelanocortin Homo sapiens