Title : Prolactin stimulates and potentiates adrenal steroid secretion in vitro.

Pub. Date : 1984

PMID : 6096247






4 Functional Relationships(s)
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1 Prolactin stimulates and potentiates adrenal steroid secretion in vitro. Steroids prolactin Rattus norvegicus
2 Prolactin, alone and in combination with ACTH, was tested for its ability to release steroids from rat adrenocortical slices superfused in vitro. Steroids prolactin Rattus norvegicus
3 Analysis of individual steroids in superfusate by RIA revealed that aldosterone release was most sensitive to prolactin, followed by corticosterone, androstenedione, and progesterone. Steroids prolactin Rattus norvegicus
4 We conclude that prolactin is an adrenocortical secretagogue of physiological relevance in the rat, and that it could play a role in enhancing the action of ACTH to acutely release steroids. Steroids prolactin Rattus norvegicus