Pub. Date : 1984 Aug
PMID : 6087679
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Antagonistic effect of theophylline on the adenosine-induced decreased in renin release. | Theophylline | renin | Canis lupus familiaris |
2 | The action of theophylline on the adenosine-induced decrease in renin release was studied in anesthetized dogs. | Theophylline | renin | Canis lupus familiaris |
3 | Theophylline (5 mumol/min intrarenally) had no significant effect on GFR or RBF yet produced a significant increase in the release of renin and the fractional excretion of sodium. | Theophylline | renin | Canis lupus familiaris |
4 | Theophylline at 5 X 10(-6) mol/min, which stimulates renin release and effectively antagonizes the renal effects of adenosine, had no detectable effect on cAMP measured in renal cortex. | Theophylline | renin | Canis lupus familiaris |
5 | These findings demonstrate that theophylline, at concentrations having no effect on cortical cAMP, antagonizes the effect of adenosine on renin release. | Theophylline | renin | Canis lupus familiaris |
6 | The results are also consistent with the view that theophylline stimulates renin release by a mechanism other than its action on cAMP. | Theophylline | renin | Canis lupus familiaris |