Title : A simple system for the investigation of protein binding effects on the renal handling of drugs in an isolated perfused rat kidney preparation.

Pub. Date : 1984 Sep

PMID : 6085642






1 Functional Relationships(s)
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1 When applied to digitoxin and frusemide, two drugs highly bound to bovine serum albumin, the fraction of drug unbound could be continuously varied over approximately a 30-fold range. Furosemide albumin Rattus norvegicus