Title : The inhibition of rat brain monoamine oxidase-B by J-508 (N-methyl-N-propargyl-(1-indanyl)-ammonium hydrochloride), and its use for the titration of this enzyme form.

Pub. Date : 1979

PMID : 547123






3 Functional Relationships(s)
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1 The inhibition of rat brain monoamine oxidase-B by J-508 (N-methyl-N-propargyl-(1-indanyl)-ammonium hydrochloride), and its use for the titration of this enzyme form. N-methyl-N-propargyl-(1-indanyl)-ammonium hydrochloride monoamine oxidase B Rattus norvegicus
2 The inhibition of rat brain monoamine oxidase-B by J-508 (N-methyl-N-propargyl-(1-indanyl)-ammonium hydrochloride), and its use for the titration of this enzyme form. N-methyl-N-propargyl-(1-indanyl)-ammonium hydrochloride monoamine oxidase B Rattus norvegicus
3 J-508 inhibits rat brain monoamine oxidase-B in a manner consistent with a "suicide" reaction, and is so potent an inhibitor that it produces inhibition at concentrations of the same order as those of the enzyme. N-methyl-N-propargyl-(1-indanyl)-ammonium hydrochloride monoamine oxidase B Rattus norvegicus