Title : Synthesis and properties of carbonylbis(methionyl)insulin, a proinsulin analogue which is convertible to insulin by cyanogen bromide cleavage.

Pub. Date : 1976 Apr 20

PMID : 5108






1 Functional Relationships(s)
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Protein Name
Organism
1 Treatment of CBM-insulin with cyanogen bromide (CNBr) in 70% formic acid for 1 h resulted in nearly complete removal of the methionine bridge to yield insulin. formic acid insulin Homo sapiens