Pub. Date : 1975 Aug
PMID : 51003
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Inhibition of IgE and compound 48/80-induced histamine release by lectins. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |
| 2 | In addition, histamine release in an IgE-mediated and a compound 48/80-mediated reaction was inhibited in cells which had been pretreated with these lectins. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |
| 3 | However, the lectin-induced histamine release and the lectin-induced inhibition of subsequent IgE-mediated histamine release could be dissociated: thus L-rhamnose, a hexose not ordinarily found on mammalian cell membranes, a specifically inhibited histamine release which was caused by the lectin from R. communis without affecting the inhibition of IgE-mediated histamine release. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |
| 4 | However, the lectin-induced histamine release and the lectin-induced inhibition of subsequent IgE-mediated histamine release could be dissociated: thus L-rhamnose, a hexose not ordinarily found on mammalian cell membranes, a specifically inhibited histamine release which was caused by the lectin from R. communis without affecting the inhibition of IgE-mediated histamine release. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |
| 5 | However, the lectin-induced histamine release and the lectin-induced inhibition of subsequent IgE-mediated histamine release could be dissociated: thus L-rhamnose, a hexose not ordinarily found on mammalian cell membranes, a specifically inhibited histamine release which was caused by the lectin from R. communis without affecting the inhibition of IgE-mediated histamine release. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |
| 6 | Conversely, D-fucose, which also is not a constituent of cell membrane glycolipids or glycoproteins prevented the inhibition of IgE-mediated histamine release by this lectin without affecting the lectin-induced histamine release. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |
| 7 | Furthermore, the nominally galactose-specific lectins from Sophora japonica and Ulex europeus inhibited IgE-mediated histamine release while causing little if any histamine release themselves. | Histamine | immunoglobulin heavy constant epsilon | Homo sapiens |