Title : An acquired abnormal fibrinogen associated with thromboembolic disease and pseudotumor cerebri.

Pub. Date : 1979 Oct 31

PMID : 505412






1 Functional Relationships(s)
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1 The fibrinogen is characterized by (1) abnormal side-to-side and end-to-end polymerization, (2) abnormal fibrinopeptide release, (3) a delayed gamma-gamma dimerization of the non cross-linked fibrin, (4) a pH optimum of 7--7.8, and (5) a deviation from normal amino acid composition with regard to lysine, aspartic acid, glutamic acid and serine. Aspartic Acid fibrinogen beta chain Homo sapiens