Pub. Date : 1979 Apr
PMID : 457783
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Tunicamycin-mediated depletion of insulin receptors in 3T3-L1 adipocytes. | Tunicamycin | insulin | Homo sapiens |
| 2 | Tunicamycin, an antibiotic that inhibits protein glycosylation, elicited a rapid depletion of insulin binding activity at the surface of 3T3-L1 adipocytes. | Tunicamycin | insulin | Homo sapiens |
| 3 | Disappearance of insulin receptors occurred more rapidly in the presence of tunicamycin than when protein synthesis was inhibited by cycloheximide and was accompanied by a diminution in sensitivity of the adipocytes to the acute effects of insulin and anti-insulin receptor antibody on hexose uptake and metabolism. | Tunicamycin | insulin | Homo sapiens |
| 4 | Disappearance of insulin receptors occurred more rapidly in the presence of tunicamycin than when protein synthesis was inhibited by cycloheximide and was accompanied by a diminution in sensitivity of the adipocytes to the acute effects of insulin and anti-insulin receptor antibody on hexose uptake and metabolism. | Tunicamycin | insulin | Homo sapiens |
| 5 | Disappearance of insulin receptors occurred more rapidly in the presence of tunicamycin than when protein synthesis was inhibited by cycloheximide and was accompanied by a diminution in sensitivity of the adipocytes to the acute effects of insulin and anti-insulin receptor antibody on hexose uptake and metabolism. | Tunicamycin | insulin | Homo sapiens |