Title : Glucocorticoid-mediated inhibition of erythroid colony formation by mouse bone marrow cells.

Pub. Date : 1979 May

PMID : 429879






2 Functional Relationships(s)
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1 In these experiments, bone marrow cells cultured in the presence of Epo (25 microU) and dexamethasone (2 X 10(-6)M to 2 X 10(-8)M) formed fewer erythroid colonies than cells cultured in the presence of Epo alone. Dexamethasone erythropoietin Mus musculus
2 These studies show therefore that dexamethasone, either in vivo or in vitro, decreases the number and/or functional capacity of adult murine bone marrow cells capable of forming erythroid colonies in vitro in response to Epo, although the precise mechanism of this inhibition remains to be established. Dexamethasone erythropoietin Mus musculus