Title : Augmentation of puerperal lactation by oral administration of sulpiride.

Pub. Date : 1979 Mar

PMID : 429499






4 Functional Relationships(s)
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1 The effect of oral administration of sulpiride on PRL secretion and initiation of puerperal lactation was studied in 130 randomly selected primiparous nursing mothers. Sulpiride prolactin Homo sapiens
2 Every other day determinations of serum PRL levels revealed significantly higher concentrations in the sulpiride group than in the control group. Sulpiride prolactin Homo sapiens
3 A single oral dose of 50 mg sulpiride raised serum PRL levels for 12 h, with a peak level at 2 h after dosing in 7 women on the second postpartum day. Sulpiride prolactin Homo sapiens
4 These data suggest that sulpiride given orally promotes the initiation of lactation in puerperal women by stimulating PRL secretion. Sulpiride prolactin Homo sapiens