Title : Synergism between thrombin and epinephrine in human platelets: different dose-response relationships for aggregation and dense granule secretion.

Pub. Date : 1985 Oct 30

PMID : 4089798






2 Functional Relationships(s)
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1 Both aggregation and secretion induced with 0.03-0.3 U/ml of thrombin were markedly potentiated by epinephrine (0.5-4 microM), which alone was without effect. Epinephrine coagulation factor II, thrombin Homo sapiens
2 Addition of epinephrine before stimulation with thrombin resulted in a marked decrease in the concentration of thrombin required for half-maximal aggregation, without affecting the maximal aggregation response. Epinephrine coagulation factor II, thrombin Homo sapiens