Pub. Date : 1985 Jul
PMID : 4059585
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Intravenous histamine reduces bombesin-stimulated gastrin release in dogs. | Histamine | gastrin | Canis lupus familiaris |
| 2 | The effect of histamine on gastrin release was studied in 7 conscious mongrel dogs with chronic gastric and duodenal fistulas. | Histamine | gastrin | Canis lupus familiaris |
| 3 | Gastrin release, as expressed by the integrated response during the last 50 min of the bombesin infusion was significantly (P less than 0.05) decreased by all doses of histamine, compared to control. | Histamine | gastrin | Canis lupus familiaris |
| 4 | The infusion doses of histamine studied, 20, 40, 80, and 160 micrograms/kg per h reduced bombesin-stimulated gastrin release 16%, 19%, 19%, and 30%, respectively. | Histamine | gastrin | Canis lupus familiaris |
| 5 | We conclude that by an H-2 mechanism, exogenous histamine reduces bombesin-stimulated gastrin release in dog. | Histamine | gastrin | Canis lupus familiaris |