Title : Mephenytoin hydroxylation polymorphism: characterization of the enzymatic deficiency in liver microsomes of poor metabolizers phenotyped in vivo.

Pub. Date : 1985 Nov

PMID : 4053486






2 Functional Relationships(s)
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1 These results support our hypothesis that the mephenytoin polymorphism is caused by a partial or complete absence or inactivity of a cytochrome P-450 isozyme with high affinity for S-mephenytoin. Mephenytoin cytochrome P450 family 4 subfamily F member 3 Homo sapiens
2 These results support our hypothesis that the mephenytoin polymorphism is caused by a partial or complete absence or inactivity of a cytochrome P-450 isozyme with high affinity for S-mephenytoin. Mephenytoin cytochrome P450 family 4 subfamily F member 3 Homo sapiens