Title : Abnormal growth hormone responses to L-dopa and thyrotropin-releasing hormone in patients with acromegaly.

Pub. Date : 1977 Mar

PMID : 404727






1 Functional Relationships(s)
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1 When this correlation is considered in connection with the reported effects of L-dopa on GH and thyroid stimulating hormne (TSH) in man, the following hypothesis might be proposed: L-dopa has two opposing actions on the hypothalamo-pituitary system; 1) inhibition of TRH release or suppression of GH release from TRH sensitive GH producing cells, and 2) arginine-like facilitation of GH release presumably via stimulation of GH-RF. Levodopa growth hormone releasing hormone Homo sapiens