Title : Induction of the insulin proreceptor by hydrocortisone in cultured lymphocytes (IM-9 line).

Pub. Date : 1985 Aug

PMID : 4031068






4 Functional Relationships(s)
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1 Induction of the insulin proreceptor by hydrocortisone in cultured lymphocytes (IM-9 line). Hydrocortisone insulin Homo sapiens
2 Hydrocortisone increases the number of insulin receptors at the surface of human cultured lymphocytes (IM-9 line) without altering the degradation of the mature receptor subunits. Hydrocortisone insulin Homo sapiens
3 The incorporation of [3H]mannose into the insulin receptor precursor and the mature subunits was detectable as early as 30 min of chase and was two to three times higher in hydrocortisone-treated cells at any time point of incubation. Hydrocortisone insulin Homo sapiens
4 Hydrocortisone represents the first pharmacologic agent shown to induce the synthesis of the insulin proreceptor. Hydrocortisone insulin Homo sapiens