Title : Role of lipid A of endotoxin in the production of tumour necrosis factor.

Pub. Date : 1985 Mar

PMID : 4000132






4 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 This release is greatly reduced by neutralisation of lipid A of LPS with the antibiotic polymyxin B sulfate. Lipid A toll-like receptor 4 Mus musculus
2 Base-hydrolysed LPS, which is devoid of lipid A, cannot induce TNF release. Lipid A toll-like receptor 4 Mus musculus
3 These results suggest that lipid A of LPS molecule is important in causing lethality and TNF release in vivo while the polysaccharide portion may be involved in delivering the lipid A moiety to TNF-producing cells. Lipid A toll-like receptor 4 Mus musculus
4 These results suggest that lipid A of LPS molecule is important in causing lethality and TNF release in vivo while the polysaccharide portion may be involved in delivering the lipid A moiety to TNF-producing cells. Lipid A toll-like receptor 4 Mus musculus