Pub. Date : 1985
PMID : 3996731
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The homogeneity of rat liver microsomal cytochrome P-448 activity and its role in the activation of benzo[a]pyrene to mutagens. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily a, polypeptide 2 | Rattus norvegicus |
| 2 | An excellent direct correlation (r = 0.95) has been observed between ethoxyresorufin O-deethylase and the metabolic activation of benzo[a]pyrene to mutagens when the fraction of cytochromes P-450 present as cytochrome P-448 was altered by the administration of phenobarbitone and 3-methylcholanthrene alone or in combination with 9-hydroxyellipticine. | Benzo(a)pyrene | cytochrome P450, family 1, subfamily a, polypeptide 2 | Rattus norvegicus |