Pub. Date : 1985 Feb 15
PMID : 3977910
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Retinoic acid treatment of human neuroblastoma cells is associated with decreased N-myc expression. | Tretinoin | MYCN proto-oncogene, bHLH transcription factor | Homo sapiens |
| 2 | We report here that N-myc mRNA content is markedly decreased in cells of a neuroblastoma cell line (LA-N-5) following differentiation induced with retinoic acid. | Tretinoin | MYCN proto-oncogene, bHLH transcription factor | Homo sapiens |
| 3 | Exposure of the cells to retinoic acid induced morphologic changes consistent with neuronal differentiation, and led to a 75% decrease in expression of N-myc mRNA. | Tretinoin | MYCN proto-oncogene, bHLH transcription factor | Homo sapiens |