Title : Gangliosides GM1 and GD1b are antigens for IgM M-protein in a patient with motor neuron disease.

Pub. Date : 1986 Apr

PMID : 3960319






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Gangliosides GM1 and GD1b are antigens for IgM M-protein in a patient with motor neuron disease. G(M1) Ganglioside myomesin 2 Homo sapiens
2 IgM-binding to the two gangliosides was detectable by ELISA at serum dilutions of greater than 1:10,000, and the M-protein was selectively immunoabsorbed by liposomes containing GM1 or GD1b. G(M1) Ganglioside myomesin 2 Homo sapiens
3 The IgM M-protein also bound to asialo-GM1, indicating reactivity to the galactosyl(beta 1-3)N-acetylgalactosaminyl moiety shared by GM1, GD1b, and asialo-GM1. G(M1) Ganglioside myomesin 2 Homo sapiens
4 The IgM M-protein also bound to asialo-GM1, indicating reactivity to the galactosyl(beta 1-3)N-acetylgalactosaminyl moiety shared by GM1, GD1b, and asialo-GM1. G(M1) Ganglioside myomesin 2 Homo sapiens