Title : [Effect of amidopyrine on the rate of cytochrome P-450 isoform breakdown].

Pub. Date : 1986 Feb

PMID : 3947732






2 Functional Relationships(s)
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1 The effect of liver monooxygenase system substrates upon the rate of cytochrome P-450 isoform degradation was investigated by measuring the half-life of liver microsomal proteins in C57BL/6 mice injected with phenobarbital and then 24 hours later with aminopyrine every 6 hours. Phenobarbital cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus
2 The rate of phenobarbital-induced degradation of cytochrome P-450 isoform (mol weight 56000 daltons) was shown to be increased two-fold. Phenobarbital cytochrome P450, family 21, subfamily a, polypeptide 1 Mus musculus