Title : Stimulation of carbonic anhydrase in osteoclasts by parathyroid hormone.

Pub. Date : 1985 Dec

PMID : 3937590






2 Functional Relationships(s)
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1 Acetazolamide, a potent inhibitor of carbonic anhydrase, inhibited the increase in fluorescence induced by PTH, but this drug was less effective in reducing fluorescence in maximally than in submaximally stimulated osteoclasts, indicating that either more enzyme or more resistant enzyme was present in the PTH-stimulated cells. Acetazolamide parathyroid hormone Homo sapiens
2 Acetazolamide, a potent inhibitor of carbonic anhydrase, inhibited the increase in fluorescence induced by PTH, but this drug was less effective in reducing fluorescence in maximally than in submaximally stimulated osteoclasts, indicating that either more enzyme or more resistant enzyme was present in the PTH-stimulated cells. Acetazolamide parathyroid hormone Homo sapiens