Title : Mepacrine (quinacrine) inhibition of thrombin-induced platelet responses can be overcome by lysophosphatidic acid.

Pub. Date : 1985 Oct 17

PMID : 3931692






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Such synthesis of lysophosphatidic acid can be inhibited by mepacrine, an inhibitor of the phospholipase A2 which attacks phosphatidic acid to give lysophosphatidic acid. lysophosphatidic acid phospholipase A2 group IB Homo sapiens
2 Such synthesis of lysophosphatidic acid can be inhibited by mepacrine, an inhibitor of the phospholipase A2 which attacks phosphatidic acid to give lysophosphatidic acid. lysophosphatidic acid phospholipase A2 group IB Homo sapiens
3 The results suggest that lysophosphatidic acid primarily acts distal to mepacrine inhibition of phospholipase A2 and phospholipase C and are consistent with the possibility that lysophosphatidic acid might be a mediator of part of the effects of low-dose thrombin on human platelets. lysophosphatidic acid phospholipase A2 group IB Homo sapiens