Title : Effect of inhibition of polyamine biosynthesis by DL-alpha-difluoromethylornithine on the growth and melanogenesis of B16 melanoma in vitro and in vivo.

Pub. Date : 1985 Sep

PMID : 3928149






1 Functional Relationships(s)
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1 Administration of different doses of DFMO in drinking water to B16 melanoma tumor bearing mice also resulted in an increase in tyrosinase activity and a dose dependent inhibition (86-90%) of tumor growth. Eflornithine tyrosinase Mus musculus