Title : Heterogeneity of holocarboxylase synthetase in patients with biotin-responsive multiple carboxylase deficiency.

Pub. Date : 1985 Mar

PMID : 3920902






3 Functional Relationships(s)
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1 Heterogeneity of holocarboxylase synthetase in patients with biotin-responsive multiple carboxylase deficiency. Biotin holocarboxylase synthetase Homo sapiens
2 Holocarboxylase synthetase activity has been determined in fibroblasts of seven patients with the neonatal form of biotin-responsive multiple carboxylase deficiency. Biotin holocarboxylase synthetase Homo sapiens
3 Differences among the values obtained for the Km for biotin and the heat stability of holocarboxylase synthetase suggested that the patients studied represented at least four distinct variants at the holocarboxylase synthetase locus. Biotin holocarboxylase synthetase Homo sapiens