Pub. Date : 1985 Aug
PMID : 3893986
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Insulin suppresses triiodothyronine-induced growth hormone secretion by GH3 rat pituitary cells. | Triiodothyronine | insulin | Homo sapiens |
| 2 | This suppression was maximal with 3.5 nM insulin and occurred after a lag period of 48 h. The previously described 20-fold synergistic stimulation of GH by T3 (0.5 nM) together with HCT (1 microM) was also suppressed by insulin (3.5 nM) by 80% during 72 h of incubation. | Triiodothyronine | insulin | Homo sapiens |
| 3 | This suppression was maximal with 3.5 nM insulin and occurred after a lag period of 48 h. The previously described 20-fold synergistic stimulation of GH by T3 (0.5 nM) together with HCT (1 microM) was also suppressed by insulin (3.5 nM) by 80% during 72 h of incubation. | Triiodothyronine | insulin | Homo sapiens |
| 4 | Alternatively, the inhibitory effects of insulin on T3-induced GH secretion in these cells may be posttranscriptional. | Triiodothyronine | insulin | Homo sapiens |