Title : Regulation of cytochrome P-450 gene expression. Studies with a cloned probe.

Pub. Date : 1985 Feb 10

PMID : 3838174






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 A cDNA clone for cytochrome P-450e, a phenobarbitone-inducible species in rat liver, has been isolated and characterized. Phenobarbital cytochrome P450, family 2, subfamily b, polypeptide 2 Rattus norvegicus
2 Inhibitors of heme synthesis such as cobalt chloride and 3-amino-1,2,4-triazole block the induction of cytochrome P-450e by phenobarbitone at the level of transcription. Phenobarbital cytochrome P450, family 2, subfamily b, polypeptide 2 Rattus norvegicus