Title : Stimulation of Ca2+ efflux from fura-2-loaded platelets activated by thrombin or phorbol myristate acetate.

Pub. Date : 1987 Jan 5

PMID : 3792558






2 Functional Relationships(s)
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1 Thrombin added shortly after ionomycin could accelerate the recovery of [Ca2+]i and restore resting levels within 5 min, an effect that was mimicked by phorbol-12-myristate-13-acetate (PMA). Ionomycin coagulation factor II, thrombin Homo sapiens
2 Since the continued presence of ionomycin precluded reuptake into the internal stores we conclude that thrombin and PMA stimulate Ca2+ efflux, perhaps via protein kinase C actions on a plasma membrane Ca2+ pump. Ionomycin coagulation factor II, thrombin Homo sapiens