Title : Inhibition of androgen receptor binding by natural and synthetic steroids in cultured human genital skin fibroblasts.

Pub. Date : 1986 Aug 15

PMID : 3762019






3 Functional Relationships(s)
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1 Inhibition of androgen receptor binding by natural and synthetic steroids in cultured human genital skin fibroblasts. Steroids androgen receptor Homo sapiens
2 The ability of various natural and synthetic steroids (some of which are widely used in clinical practice) to compete with dihydrotestosterone receptor binding in human genital skin fibroblasts was studied. Steroids androgen receptor Homo sapiens
3 Binding affinities of all other steroids to the androgen receptor were markedly lower and showed the following order of potency: estrogens (estradiol, ethinyl estradiol, diethylstilbestrol) greater than glucocorticoids as well as aromatase inhibitors and potassium canrenoate. Steroids androgen receptor Homo sapiens