Title : Changes in the expression of oncogenes encoding nuclear phosphoproteins but not c-Ha-ras have a relationship to monocytic differentiation of HL 60 cells.

Pub. Date : 1986 Jun

PMID : 3754873






2 Functional Relationships(s)
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1 The phenotypic differentiation induced by 1,25(OH)2D3 was preceded by altered expression of oncogenes c-myc and c-fos, but not of c-Ha-ras or of the constitutively expressed p72 gene. Calcitriol MYC proto-oncogene, bHLH transcription factor Homo sapiens
2 In partially resistant sublines exposure to 1,25(OH)2D3 or 5-Aza CR resulted in changes in the levels of c-myc and c-fos mRNA, but the expression of c-Ha-ras gene did not correlate with the phenotypic differentiation. Calcitriol MYC proto-oncogene, bHLH transcription factor Homo sapiens