Title : Morphine stimulates prolactin release in normal but not in castrated male rats.

Pub. Date : 1986 Mar

PMID : 3754583






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Morphine stimulates prolactin release in normal but not in castrated male rats. Morphine prolactin Rattus norvegicus
2 In normal animals, the treatment with morphine resulted in a significant increase of serum prolactin concentrations at all time intervals considered. Morphine prolactin Rattus norvegicus
3 together with the specific opioid receptor blocker naloxone (7.5 or 15 micrograms/rat) the stimulatory effect of morphine on prolactin release was diminished at 10 min, and totally blocked at 20 min. Morphine prolactin Rattus norvegicus
4 The results suggest that the presence of endogenous androgens is essential to permit the stimulatory effect of morphine on prolactin release. Morphine prolactin Rattus norvegicus