Pub. Date : 1986 May 15
PMID : 3707601
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Purified phenobarbital-induced cytochrome P-450 produced more oxide per nmole enzyme than any of the purified uninduced cytochrome P-450s. | Phenobarbital | cytochrome P450, family 21, subfamily a, polypeptide 1 | Mus musculus |
| 2 | Diethylphenylphosphine bound to oxidized purified phenobarbital-induced cytochrome P-450 and uninduced cytochrome P-450 with Ks values of 16 microM and 11-18 microM respectively. | Phenobarbital | cytochrome P450, family 21, subfamily a, polypeptide 1 | Mus musculus |
| 3 | Diethylphenylphosphine bound to oxidized purified phenobarbital-induced cytochrome P-450 and uninduced cytochrome P-450 with Ks values of 16 microM and 11-18 microM respectively. | Phenobarbital | cytochrome P450, family 21, subfamily a, polypeptide 1 | Mus musculus |
| 4 | Diethylphenylphosphine was also a competitive inhibitor of p-nitroanisole O-demethylation catalyzed by a reconstituted phenobarbital-induced cytochrome P-450-dependent monooxygenase system, with a Ki value of 5 microM. | Phenobarbital | cytochrome P450, family 21, subfamily a, polypeptide 1 | Mus musculus |