Title : 3-Methylene-substituted androgens as novel aromatization inhibitors. Evidence of a requirement for C-3 oxygen in C-19 hydroxylations.

Pub. Date : 1986 May 25

PMID : 3700413






1 Functional Relationships(s)
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1 Substitution of a methylene group for the C-3 oxygen in androstenedione, testosterone, and the corresponding 19-hydroxy and 19-oxo derivatives results in a new category of inhibitors of estrogen biosynthesis by human placental microsomes. Androstenedione complement C3 Homo sapiens