Title : Development and Evaluation of a PSMA-Targeted Nanosystem Co-Packaging Docetaxel and Androgen Receptor siRNA for Castration-Resistant Prostate Cancer Treatment.

Pub. Date : 2022 Apr 29

PMID : 35631549






2 Functional Relationships(s)
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1 Thus, to optimize DTX efficacy, continued maximum suppression of androgen levels and AR signaling is required. Docetaxel androgen receptor Homo sapiens
2 Specifically, DTX was encapsulated into the hydrophobic inner layer, and the AR siRNA was then condensed with the cationic PEI block in the hydrophilic outer layer of the PEI-PLGA polymeric micelles. Docetaxel androgen receptor Homo sapiens