Title : Cisplatin-Induced Reproductive Toxicity and Oxidative Stress: Ameliorative Effect of Kinetin.

Pub. Date : 2022 Apr 28

PMID : 35624727






1 Functional Relationships(s)
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1 In a dose-dependent manner, concomitant administration of kinetin with cisplatin significantly restored testicular oxidative stress parameters, corrected the distorted sperm quality parameters and histopathological changes, enhanced levels of serum testosterone and testicular StAR protein expression, as well as reduced the up-regulation of testicular TNF-alpha, IL-1beta, Il-6, and caspase-3, caused by cisplatin. Cisplatin interleukin 6 Homo sapiens