Title : S100B inhibition protects from chronic experimental autoimmune encephalomyelitis.

Pub. Date : 2022

PMID : 35620168






2 Functional Relationships(s)
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1 We examined the relevance of S100B and further investigated the potential of S100B-neutralizing small-molecule pentamidine in chronic experimental autoimmune encephalomyelitis. Pentamidine S100 calcium binding protein B Homo sapiens
2 Blockade of S100B by pentamidine protects against oligodendrogenesis impairment and neuroinflammation by reducing astrocyte reactivity and microglia pro-inflammatory phenotype. Pentamidine S100 calcium binding protein B Homo sapiens