Pub. Date : 2022 May 31
PMID : 35618186
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Herein, based on the statistically different NQO1 expression between cancerous and normal bladder tissues, the reactive oxygen species (ROS) activatable epirubicin prodrug and highly potent NQO1 substrate, KP372-1, was co-delivered using a GSH-responsive mucoadhesive nanocarrier. | Epirubicin | NAD(P)H quinone dehydrogenase 1 | Homo sapiens |
| 2 | After endocytosis, epirubicin could be promptly activated by the NQO1-dependent ROS production caused by KP372-1, thus specifically inhibiting the proliferation of bladder cancer cells. | Epirubicin | NAD(P)H quinone dehydrogenase 1 | Homo sapiens |