Title : Molecular Modelling and Virtual Screening to Identify New Piperazine Derivatives as Potent Human 5-HT1A Antagonists and Reuptake Inhibitors.

Pub. Date : 2022 May 24

PMID : 35611784






3 Functional Relationships(s)
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1 BACKGROUND: Serotonin/5-HT antagonist and reuptake inhibitors (SARIs) ameliorate depression by increasing the terminal 5-HT through the activation of somatodendritic 5-HT1A autoreceptors. Serotonin 5-hydroxytryptamine receptor 1A Homo sapiens
2 BACKGROUND: Serotonin/5-HT antagonist and reuptake inhibitors (SARIs) ameliorate depression by increasing the terminal 5-HT through the activation of somatodendritic 5-HT1A autoreceptors. Serotonin 5-hydroxytryptamine receptor 1A Homo sapiens
3 BACKGROUND: Serotonin/5-HT antagonist and reuptake inhibitors (SARIs) ameliorate depression by increasing the terminal 5-HT through the activation of somatodendritic 5-HT1A autoreceptors. Serotonin 5-hydroxytryptamine receptor 1A Homo sapiens