Title : GLI1 activates pro-fibrotic pathways in myelofibrosis fibrocytes.

Pub. Date : 2022 May 20

PMID : 35595725






1 Functional Relationships(s)
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1 Imaging analysis detected phosphotyrosine STAT3 in MF patients" BM fibrocytes, and transfection of fibrocytes with STAT3-siRNA or treatment with a JAK1/2 inhibitor ruxolitinib reduced GLI1 and MMP2/9 levels. ruxolitinib Janus kinase 1 Homo sapiens