Pub. Date : 2022 Jul
PMID : 35595026
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The present paper investigates the phenomenon called state-dependent memory (SDM) induced by ACPA (a selective cannabinoid CB1 receptor agonist) and 8-OH-DPAT (a nonselective 5-HT1A receptor agonist) with special focus on the role of the 5-HT1A receptor in the effects of both ACPA and 8-OH-DPAT SDM and cross state-dependent memory retrieval between ACPA and 8-OH-DPAT in a step-down inhibitory avoidance task. | 8-Hydroxy-2-(di-n-propylamino)tetralin | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
| 2 | The present paper investigates the phenomenon called state-dependent memory (SDM) induced by ACPA (a selective cannabinoid CB1 receptor agonist) and 8-OH-DPAT (a nonselective 5-HT1A receptor agonist) with special focus on the role of the 5-HT1A receptor in the effects of both ACPA and 8-OH-DPAT SDM and cross state-dependent memory retrieval between ACPA and 8-OH-DPAT in a step-down inhibitory avoidance task. | 8-Hydroxy-2-(di-n-propylamino)tetralin | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
| 3 | Pre-test administration of a 5-HT1A receptor antagonist, (S)-WAY 100135 (0.25 and 0.5 mug/mouse), 5 min before ACPA and 8-OH-DPAT dose-dependently inhibited ACPA- and 8-OH-DPAT-induced SDM, respectively. | 8-Hydroxy-2-(di-n-propylamino)tetralin | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |
| 4 | Overall, the data revealed that dorsal hippocampal 5-HT1A receptor mechanisms play a pivotal role in modulating cross state-dependent memory retrieval between ACPA and 8-OH-DPAT. | 8-Hydroxy-2-(di-n-propylamino)tetralin | 5-hydroxytryptamine (serotonin) receptor 1A | Mus musculus |