Title : Effects of arsenic on the topology and solubility of promyelocytic leukemia (PML)-nuclear bodies.

Pub. Date : 2022

PMID : 35594310






4 Functional Relationships(s)
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1 However, topological changes of PML-NBs in As3+-exposed cells have not been well-documented. Bromosuccinimide PML nuclear body scaffold Homo sapiens
2 We report that As3+-induced solubility shift underlies rapid SUMOylation of PML and late agglomeration of PML-NBs. Bromosuccinimide PML nuclear body scaffold Homo sapiens
3 These results warrant the importance of As3+- or Sb3+-induced solubility shift of PML for the regulation intranuclear dynamics of PML-NBs. Bromosuccinimide PML nuclear body scaffold Homo sapiens
4 These results warrant the importance of As3+- or Sb3+-induced solubility shift of PML for the regulation intranuclear dynamics of PML-NBs. Bromosuccinimide PML nuclear body scaffold Homo sapiens