Pub. Date : 2022 May 19
PMID : 35590119
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Candesartan Protects Against Cadmium-Induced Hepatorenal Syndrome by Affecting Nrf2, NF-kappaB, Bax/Bcl-2/Cyt-C, and Ang II/Ang 1-7 Signals. | candesartan | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 2 | Candesartan antioxidant effect was mediated by Nrf2 activation. | candesartan | NFE2 like bZIP transcription factor 2 | Homo sapiens |
| 3 | Overall, our findings revealed that candesartan could attenuate Cd-induced hepatorenal intoxication through modulation of Nrf2, NF-kappaB/IkappaB, Bax/Bcl-2/Cyt-c, and Ang II/Ang 1-7 signaling pathways. | candesartan | NFE2 like bZIP transcription factor 2 | Homo sapiens |