Title : Polycystic Ovary Syndrome and the Neuroendocrine Consequences of Androgen Excess.

Pub. Date : 2022 Mar 29

PMID : 35578968






3 Functional Relationships(s)
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1 Abnormal central gamma-aminobutyric acid (GABA) signaling has been identified in both patients and preclinical models as a possible link between androgen excess and elevated GnRH/LH secretion. gamma-Aminobutyric Acid gonadotropin releasing hormone 1 Homo sapiens
2 Abnormal central gamma-aminobutyric acid (GABA) signaling has been identified in both patients and preclinical models as a possible link between androgen excess and elevated GnRH/LH secretion. gamma-Aminobutyric Acid gonadotropin releasing hormone 1 Homo sapiens
3 Accordingly, this article also provides an overview of GABA regulation of GnRH neuron function from prenatal development to adulthood to discuss possible avenues for future discovery research and therapeutic interventions. gamma-Aminobutyric Acid gonadotropin releasing hormone 1 Homo sapiens