Title : Neutrophil Myeloperoxidase-Mediated N-Demethylation of Quetiapine Leads to N-Desalkylquetiapine, a Pharmacologically Active Cytochrome P450 Metabolite.

Pub. Date : 2022 Jun 20

PMID : 35575633






1 Functional Relationships(s)
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1 Lastly, compared to quetiapine, clozapine metabolism by MPO/H2O2 and glutathione produced more glutathionyl radicals using EPR spin trapping. glutathionyl radicals myeloperoxidase Homo sapiens