Title : Giardia intestinalis thymidine kinase is a high-affinity enzyme crucial for DNA synthesis and an exploitable target for drug discovery.

Pub. Date : 2022 May 11

PMID : 35568200






1 Functional Relationships(s)
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1 This efficient substrate discrimination is in line with the lack of thymidylate synthase and dUTPase in the parasite, which makes dUMP a dead-end product that is potentially harmful if converted to dUTP. deoxyuridine triphosphate Deoxyuridine triphosphatase Drosophila melanogaster