Title : A Novel Mechanism for SIRT1 Activators That Does Not Rely on the Chemical Moiety Immediately C-Terminal to the Acetyl-Lysine of the Substrate.

Pub. Date : 2022 Apr 22

PMID : 35566069






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 SIRT1, an NAD+-dependent deacetylase, catalyzes the deacetylation of proteins coupled with the breakdown of NAD+ into nicotinamide and 2"-O-acetyl-ADP-ribose (OAADPr). Niacinamide sirtuin 1 Homo sapiens