Title : The Inhibition of Gastric Cancer Cells' Progression by 23,24-Dihydrocucurbitacin E through Disruption of the Ras/Raf/ERK/MMP9 Signaling Pathway.

Pub. Date : 2022 Apr 22

PMID : 35566048






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The results indicated that DHCE obviously inhibited the kinase activity of ERK2 via targeting its ATP-binding domain, destroyed F-actin microfilament, and reduced the expression levels of Ras, p-c-Raf, ERK, p-ERK, and MMP9 proteins. Adenosine Triphosphate mitogen-activated protein kinase 1 Homo sapiens