Title : Fighting the Huntington's Disease with a G-Quadruplex-Forming Aptamer Specifically Binding to Mutant Huntingtin Protein: Biophysical Characterization, In Vitro and In Vivo Studies.

Pub. Date : 2022 Apr 27

PMID : 35563194






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 A set of guanine-rich aptamers able to preferentially recognize full-length huntingtin with an expanded polyglutamine tract has been recently identified, showing high efficacy in modulating the functions of the mutated protein in a variety of cell experiments. polyglutamine huntingtin Homo sapiens