Title : MYC drives aggressive prostate cancer by disrupting transcriptional pause release at androgen receptor targets.

Pub. Date : 2022 May 13

PMID : 35562350






3 Functional Relationships(s)
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1 We demonstrate that MYC overexpression significantly diminishes the androgen receptor (AR) transcriptional program (the set of genes directly targeted by the AR protein) in luminal prostate cells without altering AR expression. Phenobarbital androgen receptor Homo sapiens
2 We demonstrate that MYC overexpression significantly diminishes the androgen receptor (AR) transcriptional program (the set of genes directly targeted by the AR protein) in luminal prostate cells without altering AR expression. Phenobarbital androgen receptor Homo sapiens
3 We demonstrate that MYC overexpression significantly diminishes the androgen receptor (AR) transcriptional program (the set of genes directly targeted by the AR protein) in luminal prostate cells without altering AR expression. Phenobarbital androgen receptor Homo sapiens